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B6db activities: 2.1.2.1

2.1.2.1
Description Glycine hydroxymethyltransferase
Alternative names Serine hydroxymethyltransferase;
Serine aldolase;
Threonine aldolase;
Serine hydroxymethylase.
Catalyzed reaction 5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate + L-serine.
Cofactor Pyridoxal-phosphate.
Comments -!- Also catalyzes the reaction of glycine with acetaldehyde to form L-threonine, and with 4-trimethylammoniobutanal to form 3-hydroxy- N6,N6,N6-trimethyl-L-lysine.
Prosite PROSITE; PDOC00090;
PDB 1BJ4; 1DFO; 1EJI; 1EQB; 1KKJ; 1KKP; 1KL2;
Organisms -Eubacteria -Archea -Plants -Fungi -Metazoa -Human
 
 
Links Enzyme (activities) 2.1.2.1
BRENDA (activities) 2.1.2.1
KEGG (pathways) 2.1.2.1
PLPMDB (PLP mutants) 2.1.2.1
 
References Articles on 2.1.2.1
 
last changed 2017/10/10 14:11

B6db activities