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B6db activities: 2.3.1.29

2.3.1.29
Description Glycine C-acetyltransferase.
Alternative names 2-amino-3-ketobutyrate coenzyme A ligase.
Catalyzed reaction Acetyl-CoA + glycine = CoA + 2-amino-3-oxobutanoate.
Cofactor Pyridoxal-phosphate.
Prosite PROSITE; PDOC00518;
PDB 1FC4;
Organisms -Eubacteria -Metazoa -Human
 

Family 

2.3.1.29 (15)
 
Links Enzyme (activities) 2.3.1.29
BRENDA (activities) 2.3.1.29
KEGG (pathways) 2.3.1.29
PLPMDB (PLP mutants) 2.3.1.29
 
References
 Schmidt, A.; Sivaraman, J.; Li, Y.; Larocque, R.; Barbosa, J.A.; Smith, C.; Matte, A.; Schrag, J.D.; Cygler, M. (2001) Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from Escherichia coli complexed with a PLP-substrate intermediate: inferred reaction mechanism Biochemistry 40 5151-60.

 Edgar, A. J.; Polak, J. M. (2000) Molecular cloning of the human and murine 2-amino-3-ketobutyrate coenzyme A ligase cDNAs Eur J Biochem 267 1805-12.

 Tong, H.; Davis, L. (1994) 2-Amino-3-ketobutyrate-CoA ligase from beef liver mitochondria. Purification and partial sequence J Biol Chem 269 4057-64.

 Aronson, B.D.; Ravnikar, P.D.; Somerville, R.L. (1988) Nucleotide sequence of the 2-amino-3-ketobutyrate coenzyme A ligase (kbl) gene of E. coli Nucleic Acids Res 16 3586-7.

Articles on 2.3.1.29
 
last changed 2010/01/27 18:05

B6db activities