2.5.1.113
Description	[CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase
Alternative names	O-phospho-L-serine:thiocarboxylated [CysO sulfur-carrier protein] 2-amino-2-carboxyethyltransferase; CysM.
Catalyzed reaction	O-phospho-L-serine + [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)SH = [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine + phosphate
Cofactor	Pyridoxal-phosphate.
Comments	A pyridoxal-phosphate protein. The enzyme participates in an alternative pathway for L-cysteine biosynthesis that involves a protein-bound thiocarboxylate as the sulfide donor. The enzyme from the bacterium Mycobacterium tuberculosis also has very low activity with O3-acetyl-L-serine (cf. EC 2.5.1.65, O-phosphoserine sulfhydrylase).
Organisms	-Bacteria
Links	Enzyme (activities) 2.5.1.113 BRENDA (activities) 2.5.1.113 KEGG (pathways) 2.5.1.113 PLPMDB (PLP mutants) 2.5.1.113
References	Articles on 2.5.1.113
last changed	2014/02/25 16:53