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2.5.1.113 |
Description |
[CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase |
Alternative names |
O-phospho-L-serine:thiocarboxylated [CysO sulfur-carrier protein] 2-amino-2-carboxyethyltransferase;
CysM. |
Catalyzed reaction |
O-phospho-L-serine + [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)SH = [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine + phosphate |
Cofactor |
Pyridoxal-phosphate. |
Comments |
A pyridoxal-phosphate protein. The enzyme participates in an alternative pathway for L-cysteine biosynthesis that involves a protein-bound thiocarboxylate as the sulfide donor. The enzyme from the bacterium Mycobacterium tuberculosis also has very low activity with O3-acetyl-L-serine (cf. EC 2.5.1.65, O-phosphoserine sulfhydrylase). |
Organisms |
-Bacteria |
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Links |
Enzyme (activities) 2.5.1.113
BRENDA (activities) 2.5.1.113
KEGG (pathways) 2.5.1.113
PLPMDB (PLP mutants) 2.5.1.113
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References |
Articles on 2.5.1.113 |
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last changed |
2014/02/25 16:53 |
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