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B6db activities: 2.5.1.113

2.5.1.113
Description [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase
Alternative names O-phospho-L-serine:thiocarboxylated [CysO sulfur-carrier protein] 2-amino-2-carboxyethyltransferase;
CysM.
Catalyzed reaction O-phospho-L-serine + [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)SH = [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-cysteine + phosphate
Cofactor Pyridoxal-phosphate.
Comments A pyridoxal-phosphate protein. The enzyme participates in an alternative pathway for L-cysteine biosynthesis that involves a protein-bound thiocarboxylate as the sulfide donor. The enzyme from the bacterium Mycobacterium tuberculosis also has very low activity with O3-acetyl-L-serine (cf. EC 2.5.1.65, O-phosphoserine sulfhydrylase).
Organisms -Bacteria
 
 
Links Enzyme (activities) 2.5.1.113
BRENDA (activities) 2.5.1.113
KEGG (pathways) 2.5.1.113
PLPMDB (PLP mutants) 2.5.1.113
 
References Articles on 2.5.1.113
 
last changed 2014/02/25 16:53

B6db activities