|
|
2.5.1.76 |
Description |
Cysteate synthase |
Catalyzed reaction |
O-phospho-L-serine + sulfite = L-cysteate + phosphate. |
Cofactor |
Pyridoxal-phosphate. |
Comments |
A pyridoxal-phosphate protein. It is highly specific for O-phospho-L-serine and sulfite. The reaction proceeds through a dehydroalanine (2-aminoacrylic acid) intermediate. The enzyme from Methanosarcina acetivorans is evolutionarily related to threonine synthase (EC 4.2.3.1), but the reaction is more similar to that of O-phosphoserine sulfhydrylase (EC 2.5.1.65). |
|
In methanogens, this enzyme participates in that the biosynthesis of the essential coenzyme M (2-mercaptoethanesulfonate).
|
Organisms |
-Eubacteria -Archea |
| |
Family |
|
| |
Links |
Enzyme (activities) 2.5.1.76
BRENDA (activities) 2.5.1.76
KEGG (pathways) 2.5.1.76
PLPMDB (PLP mutants) 2.5.1.76
|
| |
References |
Articles on 2.5.1.76 |
| |
last changed |
2018/07/09 13:48 |
|