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B6db activities: 2.5.1.76

2.5.1.76
Description Cysteate synthase
Catalyzed reaction O-phospho-L-serine + sulfite = L-cysteate + phosphate.
Cofactor Pyridoxal-phosphate.
Comments A pyridoxal-phosphate protein. It is highly specific for O-phospho-L-serine and sulfite. The reaction proceeds through a dehydroalanine (2-aminoacrylic acid) intermediate. The enzyme from Methanosarcina acetivorans is evolutionarily related to threonine synthase (EC 4.2.3.1), but the reaction is more similar to that of O-phosphoserine sulfhydrylase (EC 2.5.1.65).
In methanogens, this enzyme participates in that the biosynthesis of the essential coenzyme M (2-mercaptoethanesulfonate).
Organisms -Archea
 

Family 

2.5.1.76 (5)
 
Links Enzyme (activities) 2.5.1.76
BRENDA (activities) 2.5.1.76
KEGG (pathways) 2.5.1.76
PLPMDB (PLP mutants) 2.5.1.76
 
References Articles on 2.5.1.76
 
last changed 2010/01/12 13:01

B6db activities