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B6db activities: 2.6.1.111

2.6.1.111
Description 3-aminobutanoyl-CoA transaminase
Alternative names acetoacetyl-CoA transaminase;
kat (gene name); pucG (gene name);
Catalyzed reaction 3-aminobutanoyl-CoA + 2-oxoglutarate = acetoacetyl-CoA + L-glutamate
Cofactor Pyridoxal phosphate.
Comments -!- The enzyme, found in bacteria, is part of a L-lysine degradation pathway.
-!- The enzyme is also active with other beta-amino compounds such as 3-amino-5-methylhexanoyl-CoA and 3-amino-3-phenylpropanoyl-CoA.
-!- Characterization of an amminotransferate derived from a metagenome. This enzyme may be used in a variant route for lysine fermentation.
Organisms -Eubacteria
 

Family 

2.6.1.111 (0)
 
Links Enzyme (activities) 2.6.1.111
BRENDA (activities) 2.6.1.111
KEGG (pathways) 2.6.1.111
PLPMDB (PLP mutants) 2.6.1.111
 
References
 Perret A, Lechaplais C, Tricot S, Perchat N, Vergne C, Pellé C, Bastard K, Kreimeyer A, Vallenet D, Zaparucha A, Weissenbach J, Salanoubat M. (2011) A novel acyl-CoA beta-transaminase characterized from a metagenome PLoS One. 6 e22918.

Articles on 2.6.1.111
 
last changed 2017/09/12 15:14

B6db activities