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B6db activities:
Description (S)-ureidoglycine--glyoxylate transaminase
Alternative names Ureidoglycine--glyoxylate aminotransferase ;
pucG (gene name);
Catalyzed reaction (S)-ureidoglycine + glyoxylate = N-carbamoyl-2-oxoglycine + glycine
Cofactor Pyridoxal phosphate.
Comments -!- Can also use several keto acids (e.g., 2-oxoglutarate) as amino-group acceptors.
In certain bacteria, the catalyzed reaction is part of the urate degradation pathway.
The product N-carbamoyl-2-oxoglycine is also called oxalurate.
Organisms -Eubacteria

Family (0)
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
 French JB, Ealick SE. (2010) Biochemical and structural characterization of a ureidoglycine aminotransferase in the Klebsiella pneumoniae uric acid catabolic pathway. Biochemistry 49 5975-7.

 Ramazzina, I.; Costa, R.; Cendron, L.; Berni, R.; Peracchi, A.; Zanotti, G.; Percudani, R. (2010) An aminotransferase branch point connects purine catabolism to amino acid recycling Nat Chem Biol 6 801-806.

Articles on
last changed 2018/10/17 14:39

B6db activities