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2.6.1.115 |
Description |
5-hydroxydodecatetraenal 1-aminotransferase |
Alternative names |
cpkG (gene name) |
Catalyzed reaction |
(2E,5S,6E,8E,10E)-1-aminododeca-2,6,8,10-tetraen-5-ol + pyruvate = (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + L-alanine
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Cofactor |
Pyridoxal phosphate |
Comments |
The enzyme, characterized from the bacterium Streptomyces coelicolor A3(2), participates in the biosynthesis of coelimycin P1, where it catalyses the amination of (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal. L-glutamate can also serve as the amino group donor with lower efficiency. |
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The product of the gene ArpN, in Streptomyces argillaceus, could catalyze a similar but distinct reaction in the biosynthesis of Argimycins P alkaloids. |
Organisms |
-Eubacteria |
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Family |
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Links |
Enzyme (activities) 2.6.1.115
BRENDA (activities) 2.6.1.115
KEGG (pathways) 2.6.1.115
PLPMDB (PLP mutants) 2.6.1.115
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References |
Articles on 2.6.1.115 |
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last changed |
2019/03/25 14:06 |
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