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B6db activities:
Description Glutamine--pyruvate aminotransferase
Alternative names Glutaminase II;
Glutamine--oxo-acid transaminase;
Glutamine transaminase L.
Catalyzed reaction L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine.
Cofactor Pyridoxal-phosphate.
Comments -!- L-methionine can act as donor.
-!- Glyoxylate can act as acceptor.
Activity is documented only in mammals. Bacterial sequences identified as in some databanks are misannotated and do not refer to PLP-dependent enzymes.
Organisms -Metazoa
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
 Pinto JT, Krasnikov BF, Alcutt S, Jones ME, Dorai T, Villar MT, Artigues A, Li J, Cooper AJ (2014) Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate β-lyase activity and can transaminate L-selenomethionine J Biol Chem 289 30950-61.

 Cooper, J. L.; Meister, A. (1972) Isolation and properties of highly purified glutamine transaminase Biochemistry 11 661-71.

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last changed 2018/12/20 10:55

B6db activities