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B6db activities:
Description Beta-alanine--pyruvate aminotransferase
Alternative names beta-alanine-alpha-alanine transaminase;
Omega-amino acid--pyruvate aminotransferase (ambiguous)
Catalyzed reaction L-alanine + 3-oxopropanoate = pyruvate + beta-alanine.
Cofactor Pyridoxal-phosphate.
PDB 3A8U; 4B98; 4B9B;
Organisms -Eubacteria -Plants


Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
 Zhu D, Wei Y, Yin J, Liu D, Ang EL, Zhao H, Zhang Y (2020) A pathway for degradation of uracil to acetyl coenzyme A in Bacillus megaterium Appl Environ Microbiol in press.

 Wilding M, Peat TS, Newman J, Scott C (2016) A β-Alanine Catabolism Pathway Containing a Highly Promiscuous ω-Transaminase in the 12-Aminododecanate-Degrading Pseudomonas sp. Strain AAC Appl Environ Microbiol 82 3846-56.

 Yun, H.; Lim, S.; Cho, B.K.; Kim, B.G. (2004) omega-Amino acid:pyruvate transaminase from Alcaligenes denitrificans Y2k-2: a new catalyst for kinetic resolution of beta-amino acids and amines Appl Environ Microbiol 70 2529-34.

 Yonaha, K.; Nishie, M.; Aibara, S. (1992) The primary structure of omega-amino acid:pyruvate aminotransferase J Biol Chem 267 12506-10.

 Watanabe, N. Sakabe, K. Sakabe, N. Higashi, T. Sasaki, K. Aibara, S. Morita, Y. Yonaha, K. Toyama, S. Fukutani, H. (1989) Crystal structure analysis of omega-amino acid:pyruvate aminotransferase with a newly developed Weissenberg camera and an imaging plate using synchrotron radiation J Biochem 105 1-3.

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last changed 2018/01/29 14:33

B6db activities