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2.6.1.45 |
Description |
Serine--glyoxylate aminotransferase |
Alternative names |
L-serine glyoxylate transaminase;
SGAT. |
Catalyzed reaction |
L-serine + glyoxylate = 3-hydroxypyruvate + glycine. |
Cofactor |
Pyridoxal-phosphate. |
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The Arabidopsis enzyme also shows alanine-glyoxylate aminotransferase activity (2.6.1.44), but serine is the preferred substrate. |
Prosite |
PDOC00514; |
PDB |
6PK3; |
Organisms |
-Eubacteria -Plants |
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Family |
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Links |
Enzyme (activities) 2.6.1.45
BRENDA (activities) 2.6.1.45
KEGG (pathways) 2.6.1.45
PLPMDB (PLP mutants) 2.6.1.45
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References |
But SY, Egorova SV, Khmelenina VN, Trotsenko YA (2019) Serine-glyoxylate aminotranferases from methanotrophs using different C1-assimilation pathways Antonie Van Leeuwenhoek 112 741-751. Liepman AH, Vijayalakshmi J, Peisach D, Hulsebus B, Olsen LJ, Saper MA (2019) Crystal Structure Of Photorespiratory Alanine:Glyoxylate Aminotransferase 1 (AGT1) From Arabidopsis thaliana Front Plant Sci 10 1229. Zhang Z, Mao X, Ou J, Ye N, Zhang J, Peng X (2015) Distinct photorespiratory reactions are preferentially catalyzed by glutamate:glyoxylate and serine:glyoxylate aminotransferases in rice
J Photochem Photobiol B 142 110-7. Liepman, A.H.; Olsen, L.J. (2001) Peroxisomal alanine : glyoxylate aminotransferase (AGT1) is a photorespiratory enzyme with multiple substrates in Arabidopsis thaliana.
Plant J 25 487-98. Hagishita, T.; Yoshida, T.; Izumi, Y.; Mitsunaga, T. (1996) Cloning and expression of the gene for serine-glyoxylate aminotransferase from an obligate methylotroph Hyphomicrobium methylovorum GM2 Eur J Biochem 241 1-5. Chistoserdova, L.V.; Lidstrom, M.E. (1994) Genetics of the serine cycle in Methylobacterium extorquens AM1: identification of sgaA and mtdA and sequences of sgaA, hprA, and mtdA J Bacteriol 176 1957-68. Articles on 2.6.1.45 |
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last changed |
2019/11/11 09:32 |
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