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B6db activities:
Description Phenylalanine(histidine) aminotransferase.
Catalyzed reaction L-phenylalanine + pyruvate = phenylpyruvate + L-alanine.
Cofactor Pyridoxal-phosphate.
Comments -!- L-histidine and L-tyrosine can act instead of L-phenylalanine, in the reverse reaction, L-methionine, l-serine and L-glutamine can replace L-alanine.
A phenylalanine transaminase from Pseudomonas (Paracoccus) denitrificans has been later classified as an aromatic amino acid aminotransferase (EC and is included in family
Organisms -Metazoa -Human
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
 Takagi, T.; Taniguchi, T.; Yamamoto, Y.; Shibatani, T. (1991) Molecular cloning of the L-phenylalanine transaminase gene from Paracoccus denitrificans in Escherichia coli K-12 Biotechnol Appl Biochem. 13 112-9.

 Noguchi, T.; Okuno, E.; Kido, R. (1977) Identity of rat kidney histidine-pyruvate aminotransferase with glutamine-oxo acid aminotransferase Biochem J 161 177-9.

Articles on
last changed 2009/05/07 14:31

B6db activities