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B6db activities: 2.6.1.60

2.6.1.60
Description Aromatic-amino-acid--glyoxylate aminotransferase.
Catalyzed reaction An aromatic amino acid + glyoxylate = an aromatic oxo acid + glycine.
Cofactor Pyridoxal-phosphate.
Comments -!- Phenylalanine, kynurenine, tyrosine and histidine can act as amino donors.
-!- Glyoxylate, pyruvate and hydroxypyruvate can act as amino acceptors.
An organellar enzyme (mitochondria or peroxisomes). Might be identical with kynurenine-glyoxylate transaminase (EC 2.6.1.63)
Organisms -Metazoa
 
 
Links Enzyme (activities) 2.6.1.60
BRENDA (activities) 2.6.1.60
KEGG (pathways) 2.6.1.60
PLPMDB (PLP mutants) 2.6.1.60
 
References
 Takada, Y.; Noguchi, T. (1987) Aromatic-amino acid-glyoxylate aminotransferase from rat liver Methods Enzymol 142 273-9.

 Harada I, Noguchi T, Kido R. (1978) Purification and characterization of aromatic-amino-acid-glyoxylate aminotransferase from monkey and rat liver Hoppe Seylers Z Physiol Chem. 359 481-8.

Articles on 2.6.1.60
 
last changed 2007/12/07 14:34

B6db activities