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B6db activities: 2.6.1.63

2.6.1.63
Description Kynurenine--glyoxylate aminotransferase.
Catalyzed reaction L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine.
Cofactor Pyridoxal-phosphate.
Comments -!- Acts, more slowly, on L-phenylalanine, L-histidine and L-tyrosine.
May be identical with aromatic amino acid-glyoxylate aminotransferase (EC 2.6.1.60).

The enzyme from human liver is identical to serine-pyruvate/alanine-glyoxylate aminotransferase (EC 2.6.1.51).

Organisms -Metazoa
 
 
Links Enzyme (activities) 2.6.1.63
BRENDA (activities) 2.6.1.63
KEGG (pathways) 2.6.1.63
PLPMDB (PLP mutants) 2.6.1.63
 
References
 Harada, I. (1980) Glucagon inducible kynurenine aminotransferase Wakayama Igaku (J Wakayama Med Soc) 31 61-68.

 Okuno, E.; Minatogawa, Y.; Nakamura, M.; Kamoda, N.; Nakanishi, J.; Makino, M.; Kido, R. (1980) Crystallization and characterization of human liver kynurenine-- glyoxylate aminotransferase. Identity with alanine--glyoxylate aminotransferase and serine--pyruvate aminotransferase Biochem J 189 581-90.

Articles on 2.6.1.63
 
last changed 2009/05/19 15:01

B6db activities