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B6db activities: 2.6.1.76

2.6.1.76
Description Diaminobutyrate-2-oxoglutarate transaminase.
Alternative names L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase;
2,4-diaminobutyrate 4-aminotransferase;
Diaminobutyrate transaminase;
DABA aminotransferase.
Catalyzed reaction L-2,4-diaminobutyrate + 2-oxoglutarate = L-glutamate + L-aspartic 4-semialdehyde.
Cofactor Pyridoxal-phosphate; Potassium.
Comments -!- Involved in the formation of 1,3-diaminopropane in Haemophilus influenzae and Acinetobacter baumannii.
-!- A product of the ddc gene that also encodes L-2,4-diaminobutyrate decarboxylase in Acinetobacter baumannii.
-!- Differs from EC 2.6.1.46, diaminobutyrate-pyruvate transaminase which has pyruvate as the amino-group acceptor.

This is the first enzyme in the ectoine biosynthesis pathway, the other enzymes involved being EC 2.3.1.178 and EC 4.2.1.108.
Prosite PROSITE; PDOC00519;
Organisms -Eubacteria
 

Family 

2.6.1.76 (30)
 
Links Enzyme (activities) 2.6.1.76
BRENDA (activities) 2.6.1.76
KEGG (pathways) 2.6.1.76
PLPMDB (PLP mutants) 2.6.1.76
 
References Articles on 2.6.1.76
 
last changed 2010/03/11 16:19

B6db activities