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B6db activities:
Description Putrescine aminotransferase
Alternative names putrescine-α-ketoglutarate transaminase;
putrescine:α-ketoglutarate aminotransferase;
putrescine:2-oxoglutarate aminotransferase;
putrescine transaminase.
Catalyzed reaction (1) putrescine + 2-oxoglutarate = 4-aminobutanal + L-glutamate
(2) 4-aminobutanal = 1-pyrroline (spontaneous)
Cofactor Pyridoxal-phosphate.
Comments A pyridoxal-phosphate protein. The product, 4-aminobutanal, spontaneously cyclizes to form 1-pyrroline, which is a substrate for EC, 1-pyrroline dehydrogenase. Cadaverine and spermidine can also act as substrates. Forms part of the arginine-catabolism pathway.
There is an overlap between this newly-classified activity and Diamine aminotransferase ( The only function-verified gene (from E. coli) has been introduced into this database in the family.
Organisms -Eubacteria
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
 Samsonova, N.N.; Smirnov, S.V.; Altman, I.B.; Ptitsyn, L.R. (2003) Molecular cloning and characterization of Escherichia coli K12 ygjG gene BMC Microbiology 3 2.

Articles on
last changed 2010/02/02 10:28

B6db activities