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B6db activities: 4.1.1.14

4.1.1.14
Description Valine decarboxylase
Alternative names Leucine decarboxylase (ambiguous).
Catalyzed reaction L-valine = 2-methylpropanamine + CO(2).
Cofactor Pyridoxal-phosphate.
Comments -!- Also acts on L-leucine.
The functionally validated enzyme from Echinacea purpurea also acts on isoleucine.
Organisms -Eubacteria -Plants
 

Family 

 
Links Enzyme (activities) 4.1.1.14
BRENDA (activities) 4.1.1.14
KEGG (pathways) 4.1.1.14
PLPMDB (PLP mutants) 4.1.1.14
 
References
 Rizhsky L, Jin H, Shepard MR, Scott HW, Teitgen AM, Perera MA, Mhaske V, Jose A, Zheng X, Crispin M, Wurtele ES, Jones D, Hur M, Góngora-Castillo E, Buell CR, Minto RE, Nikolau BJ (2016) Integrating metabolomics and transcriptomics data to discover a biocatalyst that can generate the amine precursors for alkamide biosynthesis Plant J 88 775-793.

 Garg RP, Ma Y, Hoyt JC, Parry RJ (2002) Molecular characterization and analysis of the biosynthetic gene cluster for the azoxy antibiotic valanimycin Mol Microbiol. 46 505-17.

Articles on 4.1.1.14
 
last changed 2017/11/10 15:01

B6db activities