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B6db activities: 4.1.1.25

4.1.1.25
Description Tyrosine decarboxylase.
Catalyzed reaction L-tyrosine = tyramine + CO(2).
Cofactor Pyridoxal-phosphate.
Comments -!- The bacterial enzyme also acts on 3-hydroxytyrosine and, more slowly, on 3-hydroxyphenylalanine.
This entry does not include plant enzymes with tyrosine decarboxylase activity, which have been included into EC 4.1.1.28 (Aromatic amino acid decarboxylase).
Prosite PROSITE; PDOC00329;
PDB 3F9T;
Organisms -Bacteria -Archea -Plants
 

Family 

 
Links Enzyme (activities) 4.1.1.25
BRENDA (activities) 4.1.1.25
KEGG (pathways) 4.1.1.25
PLPMDB (PLP mutants) 4.1.1.25
 
References
 Arena ME, Fiocco D, Manca de Nadra MC, Pardo I, Spano G. (2007) Characterization of a Lactobacillus plantarum strain able to produce tyramine and partial cloning of a putative tyrosine decarboxylase gene Curr Microbiol 55 205-10.

 Marcobal A, de las Rivas B, Muñoz R. (2006) First genetic characterization of a bacterial beta-phenylethylamine biosynthetic enzyme in Enterococcus faecium RM58 FEMS Microbiol Lett 258 144-9.

 Kezmarsky, N.D; Xu, H.; Graham, D.E.; White, R.H. (2005) Identification and characterization of a l-tyrosine decarboxylase in Methanocaldococcus jannaschii Biochim Biophys Acta 1722 175-182.

 Fernández M, Linares DM, Alvarez MA. (2004) Sequencing of the tyrosine decarboxylase cluster of Lactococcus lactis IPLA 655 and the development of a PCR method for detecting tyrosine decarboxylating lactic acid bacteria J Food Prot 67 2521-9.

 Connil, N.; Le Breton, Y.; Dousset, X.; Auffray, Y.; Rince, A.; Prevost, H. (2002) Identification of the Enterococcus faecalis tyrosine decarboxylase operon involved in tyramine production Appl Environ Microbiol 68 3537-44.

 Lucas, P.; Lonvaud-Funel, A. (2002) Purification and partial gene sequence of the tyrosine decarboxylase of Lactobacillus brevis IOEB 9809 FEMS Microbiol Lett 211 85-9.

Articles on 4.1.1.25
 
last changed 2009/06/30 14:31

B6db activities