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4.1.1.86 |
Description |
Diaminobutyrate decarboxylase |
Alternative names |
DABA decarboxylase; L-2,4-diaminobutyrate decarboxylase. |
Catalyzed reaction |
L-2,4-diaminobutyrate = 1,3-diaminopropane + CO(2). |
Cofactor |
Pyridoxal-phosphate; divalent metal ion |
Comments |
-!- N(4)-acetyl-L-2,4-diaminobutanoate, 2,3-diaminopropanoate, ornithine and lysine are not substrates.
-!-In Acinetobacter baumannii it is cotranscribed with the neighboring dat gene that encodes EC 2.6.1.76, which can supply the substrate for the decarboxylase.
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PDB |
2QMA; |
Organisms |
-Eubacteria |
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Family |
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Links |
Enzyme (activities) 4.1.1.86
BRENDA (activities) 4.1.1.86
KEGG (pathways) 4.1.1.86
PLPMDB (PLP mutants) 4.1.1.86
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References |
Yamamoto, S.; Mutoh, N.; Tsuzuki, D.; Ikai, H.; Nakao, H.; Shinoda, S.; Narimatsu, S.; Miyoshi, S.I.
(2000) Cloning and characterization of the ddc homolog encoding L-2,4-diaminobutyrate decarboxylase in Enterobacter aerogenes Biol Pharm Bull 23 649-53. Ikai, H.; Yamamoto, S. (1996) Sequence analysis of the gene encoding a novel L-2,4-diaminobutyrate decarboxylase of Acinetobacter baumannii: similarity to the group II amino acid decarboxylases Arch Microbiol 166 128-31. Articles on 4.1.1.86 |
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last changed |
2019/06/21 13:12 |
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