B6db activities : 4_1_1

	Activities \| Families \| Sequences \| Fold types \| References \| Help


	4.1.1.96
Description	Carboxynorspermidine decarboxylase
Alternative names	nspC; CANS DC; Carboxyspermidine decarboxylase.
Catalyzed reaction	Carboxynorspermidine <=> bis(3-aminopropyl)amine + CO(2) Carboxyspermidine <=> spermidine + CO(2)
Cofactor	Pyridoxal-phosphate
Comments	Part of a bacterial polyamine biosynthesis pathway. The enzyme is essential for biofilm formation in the bacterium Vibrio cholerae. The enzyme from Campylobacter jejuni only produces spermidine in vivo even though it shows activity with carboxynorspermidine in vitro.
	This is the last enzyme in the biosynthesis of norspermidine, a polyamine similar to the more common spermidine. Norspermidine has been found to occur naturally in some species of bacteria as well as in plants.
PDB	3N29;
Organisms	-Eubacteria
Family	4.1.1.96 (0)

Links	Enzyme (activities) 4.1.1.96 BRENDA (activities) 4.1.1.96 KEGG (pathways) 4.1.1.96 PLPMDB (PLP mutants) 4.1.1.96

References	Articles on 4.1.1.96

last changed	2014/03/20 13:20

Family