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4.1.1.96 |
Description |
Carboxynorspermidine decarboxylase |
Alternative names |
nspC; CANS DC; Carboxyspermidine decarboxylase. |
Catalyzed reaction |
Carboxynorspermidine <=> bis(3-aminopropyl)amine + CO(2)
Carboxyspermidine <=> spermidine + CO(2) |
Cofactor |
Pyridoxal-phosphate |
Comments |
Part of a bacterial polyamine biosynthesis pathway.
The enzyme is essential for biofilm formation in the bacterium Vibrio cholerae.
The enzyme from Campylobacter jejuni only produces spermidine in vivo even though it shows activity with carboxynorspermidine in vitro. |
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This is the last enzyme in the biosynthesis of norspermidine, a polyamine similar to the more common spermidine. Norspermidine has been found to occur naturally in some species of bacteria as well as in plants. |
PDB |
3N29; |
Organisms |
-Eubacteria |
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Family |
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Links |
Enzyme (activities) 4.1.1.96
BRENDA (activities) 4.1.1.96
KEGG (pathways) 4.1.1.96
PLPMDB (PLP mutants) 4.1.1.96
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References |
Articles on 4.1.1.96 |
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last changed |
2014/03/20 13:20 |
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