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B6db activities: 4.1.2.48

4.1.2.48
Description low-specificity L-threonine aldolase
Alternative names L-threonine/L-allo-threonine acetaldehyde-lyase (glycine-forming);
LtaE.
Catalyzed reaction L-threonine = glycine + acetaldehyde L-allo-threonine = glycine + acetaldehyde
Cofactor Pyridoxal-phosphate.
Comments Requires pyridoxal phosphate. The low-specificity L-threonine aldolase can act on both L-threonine and L-allo-threonine. The enzyme from Escherichia coli can also act on L-threo-phenylserine and L-erythro-phenylserine. The enzyme can also catalyse the aldol condensation of glycolaldehyde and glycine to form 4-hydroxy-L-threonine, an intermediate of pyridoxal phosphate biosynthesis. Different from EC 4.1.2.5, L-threonine aldolase, and EC 4.1.2.49, L-allo-threonine aldolase.
Organisms -Bacteria
 
 
Links Enzyme (activities) 4.1.2.48
BRENDA (activities) 4.1.2.48
KEGG (pathways) 4.1.2.48
PLPMDB (PLP mutants) 4.1.2.48
 
References Articles on 4.1.2.48
 
last changed 2014/02/19 10:44

B6db activities