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B6db activities: 4.1.3.41

4.1.3.41
Description 3-hydroxy-D-aspartate aldolase
Alternative names D-3-hydroxyaspartate aldolase;
3-hydroxy-D-aspartate glyoxylate-lyase (glycine-forming)
Catalyzed reaction threo-3-hydroxy-D-aspartate = glycine + glyoxylate
D-erythro-3-hydroxyaspartate = glycine + glyoxylate
Cofactor Pyridoxal-phosphate.
Comments A pyridoxal-phosphate protein. The enzyme, purified from the bacterium Paracoccus denitrificans IFO 13301, is strictly D-specific as to the α-position of the substrate, but accepts both the threo anderythro forms at the β-position. The erythro form is a far better substrate (about 100 fold). The enzyme can also accept D-allothreonine, D-threonine, erythro-3-phenyl-D-serine and threo-3-phenyl-D-serine. Different from EC 4.1.3.14, erythro-3-hydroxy-L-aspartate aldolase. Requires a divalent cation, such as Mg2+, Mn2+ or Co2+.
Organisms -Eubacteria
 

Family 

4.1.3.41 (11)
 
Links Enzyme (activities) 4.1.3.41
BRENDA (activities) 4.1.3.41
KEGG (pathways) 4.1.3.41
PLPMDB (PLP mutants) 4.1.3.41
 
References Articles on 4.1.3.41
 
last changed 2014/02/24 11:56

B6db activities