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B6db activities:
Description 3-amino-5-hydroxybenzoic acid synthase
Alternative names 3-amino-5-hydroxybenzoate synthase;
AHBA synthase
Catalyzed reaction 5-amino-5-deoxy-3-dehydroshikimate <=> 3-amino-5-hydroxybenzoate + H(2)O
Cofactor Pyridoxal-phosphate.
Comments The enzyme from the bacterium Amycolatopsis mediterranei participates in the pathway for rifamycin B biosynthesis. The enzyme also functions as a transaminase earlier in the pathway, producing UDP-alpha-D-kanosamine.
3-amino-5-hydroxybenzoic acid (AHBA) serves as starter for the assembly of the polyketide backbone of several antibiotics, such as rifamycin and ansamycin.
Organisms -Eubacteria -Archea

Family (0)
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
References Articles on
last changed 2014/02/19 11:43

B6db activities