Activities | Families | Sequences | Fold types | References | Help
B6db activities: 4.2.3.134

4.2.3.134
Description 5-phosphonooxy-L-lysine phospho-lyase
Alternative names 5-phosphohydroxy-L-lysine ammoniophospholyase;
(5R)-5-phosphonooxy-L-lysine phosphate-lyase (deaminating;(S)-2-amino-6-oxohexanoate-forming)
Catalyzed reaction (5R)-5-phosphonooxy-L-lysine + H2O = (S)-2-amino-6-oxohexanoate + NH3 + phosphate
Cofactor Pyridoxal-phosphate.
Comments A pyridoxal-phosphate protein. Has no activity with phosphoethanolamine (cf. EC 4.2.3.2, ethanolamine-phosphate phospho-lyase).
Organisms -Eubacteria
 

Family 

4.2.3.134 (10)
 
Links Enzyme (activities) 4.2.3.134
BRENDA (activities) 4.2.3.134
KEGG (pathways) 4.2.3.134
PLPMDB (PLP mutants) 4.2.3.134
 
References
 Veiga-da-Cunha, M., Hadi, F., Balligand, T., Stroobant, V. and Van Schaftingen, E. (2012) Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine. J. Biol. Chem. J. Biol. Chem. 287 7246-7255.

 Tsai, C.H. and Henderson, L.M. (1974) Degradation of O-phosphohydroxylysine by rat liver. Purification of the phospho-lyase. J. Biol. Chem. 249 5784-5789.

Articles on 4.2.3.134
 
last changed 2014/02/24 11:58

B6db activities