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B6db activities:
Description Ethanolamine-phosphate phospho-lyase
Catalyzed reaction Ethanolamine phosphate + H(2)O = acetaldehyde + NH(3) + phosphate.
Cofactor Pyridoxal-phosphate.
Comments -!- Also acts on D- (or L)-1-aminopropan-2-ol O-phosphate.
-!- Formerly EC
Organisms -Eubacteria -Metazoa -Human

Family (17)
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
 Cuetos A, Steffen-Munsberg F, Mangas Sanchez J, Frese A, Bornscheuer UT, Höhne M, Grogan G (2016) Structural Basis for Phospholyase Activity of a Class III Transaminase Homologue Chembiochem 17 2308-2311.

 Schiroli, D.; Cirrincione, S.; Donini, S.; Peracchi, A. (2013) Strict reaction and substrate specificity of AGXT2L1, the human O-phosphoethanolamine phospho-lyase IUBMB Life 65 645-50.

 Veiga-da-Cunha, M., Hadi, F., Balligand, T., Stroobant, V. and Van Schaftingen, E. (2012) Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine. J. Biol. Chem. 287 7246-7255.

 Fleshood, H. L.; Pitot, H. C. (1970) The metabolism of O-phosphorylethanolamine in animal tissues. I. O- phosphorylethanolamine phospho-lyase: partial purification and characterization J Biol Chem 245 4414-20.

Articles on
last changed 2019/02/13 15:55

B6db activities