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B6db activities: 4.3.1.9

4.3.1.9
Description Glucosaminate ammonia-lyase.
Alternative names 2-amino-2-deoxy-D-gluconate ammonia-lyase;
2-amino-2-deoxy-D-gluconate hydro-lyase (deaminating);
Acetylenemonocarboxylic acid hydrase;
Aminodeoxygluconate ammonia-lyase;
Aminodeoxygluconate dehydratase;
D-glucosaminate dehydratase;
D-glucosaminic acid dehydrase;
Glucosaminic dehydrase.
Catalyzed reaction D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH(3).
Cofactor Pyridoxal-phosphate.
The enzyme from Pseudomonas fluorescens reportedly encompasses two types of subunits (alpha and beta). The alpha-subunit was sequenced and found highly similar to several thioredoxin reductases (TrxR) from bacteria.
Organisms -Eubacteria
 
 
Links Enzyme (activities) 4.3.1.9
BRENDA (activities) 4.3.1.9
KEGG (pathways) 4.3.1.9
PLPMDB (PLP mutants) 4.3.1.9
 
References
 Iwamoto R, Amano C, Ikehara K, Ushida N. (2003) The D-glucosaminate dehydratase alpha-subunit from Pseudomonas fluorescens exhibits thioredoxin reductase activity Biochim Biophys Acta 1647 310-4.

 Iwamoto, R.; Taniki, H.; Koishi, J.; Nakura, S. (1995) D-glucosaminate aldolase activity of D-glucosaminate dehydratase from Pseudomonas fluorescens and its requirement for Mn2+ ion Biosci Biotechnol Biochem 59 408-11.

 Iwamoto, R.; Imanaga, Y.; Soda, K. (1982) D-glucosaminate dehydratase from Agrobacterium radiobacter. Physicochemical and enzymological properties J Biochem (Tokyo) 91 283-9.

Articles on 4.3.1.9
 
last changed 2010/01/27 17:43

B6db activities