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B6db activities: 4.4.1.14

4.4.1.14
Description 1-aminocyclopropane-1-carboxylate synthase.
Alternative names 1-aminocyclopropane-1-carboxylic acid synthase;
Aminocyclopropanecarboxylate synthase;
ACC synthase.
Catalyzed reaction S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + methylthioadenosine.
Cofactor Pyridoxal-phosphate.
Comments -!- Catalyzes an alpha, gamma-elimination.
The enzyme carries out the rate-limiting step in the ethylene biosynthetic pathway in plants.
Prosite PROSITE; PDOC00098;
PDB 1IAY; 1IAX; 1B8G;
Organisms -Plants -Fungi
 

Family 

4.4.1.14 (19)
 
Links Enzyme (activities) 4.4.1.14
BRENDA (activities) 4.4.1.14
KEGG (pathways) 4.4.1.14
PLPMDB (PLP mutants) 4.4.1.14
 
References
 Wang D, Fan J, Ranu RS. (2004) Cloning and expression of 1-aminocyclopropane-1-carboxylate synthase cDNA from rosa (Rosa x hybrida) Plant Cell Rep 22 422-9.

 Kakuta, Y.; Igarashi, T.; Murakami, T.; Ito, H.; Matsui, H.; Honma, M. (2001) 1-Aminocyclopropane-1-carboxylate synthase of Penicillium citrinum: primary structure and expression in Escherichia coli and Saccharomyces cerevisiae Biosci Biotechnol Biochem 65 1511-8.

 Capitani G.; Hohenester, E.; Feng, L.; Storici, P.; Kirsch, J.F.; Jansonius, J.N. (1999) Structure of 1-aminocyclopropane-1-carboxylate synthase, a key enzyme in the biosynthesis of the plant hormone ethylene J Mol Biol 294 745-56.

 Sato, T.; Oeller, P. W.; Keller, J. A.; Theologis, A. (1991) The 1-aminocyclopropane-1-carboxylate synthase of Cucurbita. Purification, properties, expression in Escherichia coli, and primary structure determination by DNA sequence analysis J Biol Chem 266 3752-9.

 Van der Straeten, D.; Van Wiemeersch, L.; Goodman, H. M.; Van Montagu, M. (1990) Cloning and sequence of two different cDNAs encoding 1-aminocyclopropane-1-carboxylate synthase in tomato Proc Natl Acad Sci U S A 87 4859-63.

Articles on 4.4.1.14
 
last changed 2009/07/01 14:18

B6db activities