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B6db activities: 4.4.1.2

4.4.1.2
Description Homocysteine desulfhydrase
Alternative names Homocysteine desulfurase;
Homocysteine alpha-,gamma-lyase.
Catalyzed reaction L-homocysteine + H(2)O = H(2)S + NH(3) + 2-oxobutanoate.
Cofactor Pyridoxal-phosphate.
Comments The known enzymes catalyzing this reaction (e.g., an enzyme from Trichomonas vaginalis) also possess a substantial methionine gamma-lyase activity.
The corresponding sequences have been therefore grouped in family 4.4.1.11.
Organisms -Eubacteria -Metazoa
 
 
Links Enzyme (activities) 4.4.1.2
BRENDA (activities) 4.4.1.2
KEGG (pathways) 4.4.1.2
PLPMDB (PLP mutants) 4.4.1.2
 
References Articles on 4.4.1.2
 
last changed 2019/06/20 13:24

B6db activities