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B6db activities: 4.4.1.4

4.4.1.4
Description Alliin lyase.
Alternative names Alliinase;
Cysteine sulphoxide lyase;
L-cysteine sulfoxide lyase.
Catalyzed reaction An S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2 aminocrylate.
Cofactor Pyridoxal-phosphate.
Comments The enzyme acts in the biochemical pathway leading to the compounds responsible for the characteristic flavor of garlic and onion.
Additional_domain ALLN_ALLCE 125-450
PDB 1LK9;
Organisms -Plants
 

Family 

4.4.1.4 (7)
 
Links Enzyme (activities) 4.4.1.4
BRENDA (activities) 4.4.1.4
KEGG (pathways) 4.4.1.4
PLPMDB (PLP mutants) 4.4.1.4
 
References
 Kuettner, E.; Hilgenfeld, R.; Weiss, M. S. (2002) The active principle of garlic at atomic resolution J Biol Chem 277 46402-7.

 Lancaster, J. E.; Shaw, M. L.; Joyce, M. D.; McCallum, J. A.; McManus, M. T. (2000) A novel alliinase from onion roots. Biochemical characterization and cDNA cloning Plant Physiol 122 1269-79.

 Manabe, T.; Hasumi, A.; Sugiyama, M.; Yamazaki, M.; Saito, K. (1998) Alliinase [S-alk(en)yl-L-cysteine sulfoxide lyase] from Allium tuberosum (Chinese chive)--purification, localization, cDNA cloning and heterologous functional expression Eur J Biochem 257 21-30.

 Rabinkov, A.; Zhu, X. Z.; Grafi, G.; Galili, G.; Mirelman, D. (1994) Alliin lyase (Alliinase) from garlic (Allium sativum). Biochemical characterization and cDNA cloning Appl Biochem Biotechnol 48 149-71.

Articles on 4.4.1.4
 
last changed 2009/07/01 10:59

B6db activities