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B6db activities: 5.4.3.2

5.4.3.2
Description Lysine 2,3-aminomutase.
Catalyzed reaction L-lysine = (3S)-3,6-diaminohexanoate.
Cofactor Pyridoxal-phosphate. S-adenosyl-L-methionine; [4Fe-4S] cluster
Comments -!- Activity is stimulated by S-adenosyl-L-methionine and pyridoxal- phosphate.
An enzyme involved in one possible L-Lys degradation pathway.
The mechanism of the reaction has been delineated as a radical isomerization, in which radical formation is initiated by the [4Fe-4S]-dependent cleavage of the SAM into methionine and the 5'-deoxyadenosyl radical.
PDB 2A5H;
Organisms -Eubacteria -Archea
 

Family 

5.4.3.2 (12)
 
Links Enzyme (activities) 5.4.3.2
BRENDA (activities) 5.4.3.2
KEGG (pathways) 5.4.3.2
PLPMDB (PLP mutants) 5.4.3.2
 
References Articles on 5.4.3.2
 
last changed 2010/02/02 10:18

B6db activities