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5.4.3.5 |
Description |
D-ornithine 4,5-aminomutase |
Catalyzed reaction |
D-ornithine = D-threo-2,4-diaminopentanoate. |
Cofactor |
Pyridoxal-phosphate; Cobalamin; Dithiothreitol. |
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D-Ornithine aminomutase from Clostridium sticklandii comprises two strongly associating subunits, OraS (12800 Da) and OraE (82,900 Da). OraE is a PLP-dependent enzyme, and the C-terminal region of this protein is homologous to lysine 5,6 aminomutase (5.4.3.4) |
PDB |
3KOW; 3KP1; |
Organisms |
-Eubacteria |
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Family |
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Links |
Enzyme (activities) 5.4.3.5
BRENDA (activities) 5.4.3.5
KEGG (pathways) 5.4.3.5
PLPMDB (PLP mutants) 5.4.3.5
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References |
Chen HP, Hsui FC, Lin LY, Ren CT, Wu SH. (2004) Coexpression, purification and characterization of the E and S subunits of coenzyme B(12) and B(6) dependent Clostridium sticklandii D-ornithine aminomutase in Escherichia coli Eur J Biochem 271 4293-7. Chen, H. P.; Wu, S. H.; Lin, Y. L.; Chen, C. M.; Tsay, S. S. (2001) Cloning, sequencing, heterologous expression, purification, and characterization of adenosylcobalamin-dependent D-ornithine aminomutase from Clostridium sticklandii J Biol Chem 276 44744-50. Articles on 5.4.3.5 |
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last changed |
2019/06/20 13:37 |
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