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B6db activities: 5.4.3.9

5.4.3.9
Description Glutamate 2,3-aminomutase
Catalyzed reaction L-glutamate <=> 3-aminopentanedioate
Cofactor Pyridoxal-phosphate. S-adenosyl-L-methionine; [4Fe-4S] cluster
Comments This enzyme is a member of the 'AdoMet radical' (radical SAM) family. It contains pyridoxal phosphate and a [4Fe-4S] cluster, which is coordinated by 3 cysteines and binds an exchangeable S-adenosyl-L- methionine molecule. During the reaction cycle, the AdoMet forms a 5'-deoxyadenosyl radical, which is regenerated at the end of the reaction.
Organisms -Eubacteria
 

Family 

5.4.3.9 (8)
 
Links Enzyme (activities) 5.4.3.9
BRENDA (activities) 5.4.3.9
KEGG (pathways) 5.4.3.9
PLPMDB (PLP mutants) 5.4.3.9
 
References
 Ruzicka, F.J.; Frey, P. A. (2007) Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes Biochim Biophys Acta 1774 286-96.

Articles on 5.4.3.9
 
last changed 2014/02/19 11:46

B6db activities