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B6db activities: 2.6.1.82

2.6.1.82
Description Putrescine aminotransferase
Alternative names putrescine-α-ketoglutarate transaminase;
YgjG;
putrescine:α-ketoglutarate aminotransferase;
PAT;
putrescine:2-oxoglutarate aminotransferase;
putrescine transaminase.
Catalyzed reaction (1) putrescine + 2-oxoglutarate = 4-aminobutanal + L-glutamate
(2) 4-aminobutanal = 1-pyrroline (spontaneous)
Cofactor Pyridoxal-phosphate.
Comments A pyridoxal-phosphate protein. The product, 4-aminobutanal, spontaneously cyclizes to form 1-pyrroline, which is a substrate for EC 1.5.1.35, 1-pyrroline dehydrogenase. Cadaverine and spermidine can also act as substrates. Forms part of the arginine-catabolism pathway.
There is an overlap between this newly-classified activity and Diamine aminotransferase (2.6.1.29). The only function-verified gene (from E. coli) has been introduced into this database in the 2.6.1.29 family.
Organisms -Eubacteria
 
 
Links Enzyme (activities) 2.6.1.82
BRENDA (activities) 2.6.1.82
KEGG (pathways) 2.6.1.82
PLPMDB (PLP mutants) 2.6.1.82
 
References
 Samsonova, N.N.; Smirnov, S.V.; Altman, I.B.; Ptitsyn, L.R. (2003) Molecular cloning and characterization of Escherichia coli K12 ygjG gene BMC Microbiol 3 2.

Articles on 2.6.1.82
 
last changed 2010/02/02 10:28

B6db activities