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B6db activities:
Description 8-amino-7-oxononanoate synthase.
Alternative names AONS;
8-amino-7-ketopelargonate synthase;
7-keto-8-amino-pelargonic acid synthetase.;
7-KAP synthetase.
alpha-Oxoamine Synthase (ambiguous).
Catalyzed reaction 6-carboxyhexanoyl-CoA + L-alanine = 8-amino-7-oxononanoate + CoA + CO(2).
Cofactor Pyridoxal-phosphate.
Comments The known enzymes with this activity show a strict phylogenetic relationship to glycine acetyltransferases (EC
Indeed, some of these enzymes possess a broad substrate specificity, performing also the glycine acetyltransferase reaction.
Prosite PROSITE; PDOC00518;
PDB 1DJE; 1DJ9; 1BS0;
Organisms -Eubacteria -Archaebacteria -Plants -Fungi

Family (30)
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
References Articles on
last changed 2009/07/07 11:58

B6db activities