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B6db activities: 2.4.1.1

2.4.1.1
Description Phosphorylase
Alternative names Muscle phosphorylase A and B;
Amylophosphorylase;
Polyphosphorylase.
Catalyzed reaction {(1,4)-alpha-D-glucosyl}(N) + phosphate = {(1,4)-alpha-D-glucosyl}(N-1) + alpha-D-glucose 1-phosphate.
Cofactor Pyridoxal-phosphate.
Comments -!- The recommended name should be qualified in each instance by adding the name of the natural substance, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase.
Phosphorylases are unusual PLP-dependent enzymes, in that the reactive part of the cofactor is not the aromatic aldehyde moiety, but rather the phosphate group, which functions as a general acid/base catalyst.
Diseases Glycogen storage diseases V and VI.
Prosite PROSITE; PDOC00095;
PDB 1GPB; 7GPB; 1ABB; 1AHP; 1L5W; 1LWN;
Organisms -Eubacteria -Archea -Plants -Fungi -Metazoa -Human
 
 
Links Enzyme (activities) 2.4.1.1
BRENDA (activities) 2.4.1.1
KEGG (pathways) 2.4.1.1
PLPMDB (PLP mutants) 2.4.1.1
 
References Articles on 2.4.1.1
 
last changed 2018/05/24 13:30

B6db activities