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B6db activities:
Description L-mimosine synthase
Catalyzed reaction O3-acetyl-L-serine + 3,4-dihydroxypyridine = 3-(3,4-dihydroxypyridin- 1-yl)-L-alanine + acetate.
Cofactor Pyridoxal-phosphate.
Comments -!- Brings about the biosynthesis of L-mimosine in mimosa and Leucaena sp.
-!- Not identical with EC

Formerly EC

The only functionally validated sequence (from Leucaena leucocephala) is in fact a cysteine synthase possessing also a secondary activity as mimosine synthase.
The protein has been included in family
Organisms -Plants
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
 Md Harun-Ur-Rashid, Iwasaki H, Parveen S, Oogai S, Fukuta M, Hossain M, Anai T, Oku H (2018) Cytosolic Cysteine Synthase Switch Cysteine and Mimosine Production in Leucaena leucocephala Appl Microbiol Biotechnol. 186 613-632.

 Yafuso JT1, Negi VS, Bingham JP, Borthakur D. (2014) An O-Acetylserine (thiol) Lyase from Leucaena leucocephala Is a Cysteine Synthase But Not a Mimosine Synthase Appl Microbiol Biotechnol. 173 1157-68.

 Saito, K.; Kimura, N.; Ikegami, F.; Noji, M. (1997) Production of plant non-protein amino acids by recombinant enzymes of sequential biosynthetic reactions in bacteria Biol Pharm Bull 20 47-53.

 Murakoshi, I.; Ikegami, F.; Hinuma, Y.; Hanma, Y. (1984) Purification and characterization of L-mimosine synthase from Leucaena leucocephala Phytochemistry 23 1905-1908.

Articles on
last changed 2018/10/23 12:13

B6db activities