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2.6.1.110 |
Description |
dTDP-4-dehydro-2,3,6-trideoxy-D-glucose 4-aminotransferase |
Alternative names |
dTDP-4-dehydro-2,3,6-trideoxy-D-glucose--glutamate aminotransferase;
dTDP-4-amino-2,3,4,6-tetradeoxy-β-D-threo-hexopyranose-oxoglutarate aminotransferase;
spnR (gene name) |
Catalyzed reaction |
dTDP-4-dehydro-2,3,6-trideoxy-D-glucose + L-glutamate = dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose + 2-oxoglutarate |
Cofactor |
Pyridoxal phosphate. |
Comments |
The enzyme, isolated from the bacterium Saccharopolyspora spinosa, participates in the biosynthesis of forosamine. |
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Forosamine is a highly deoxygenated sugar found in several natural products, such as the insecticide spinosyns.
The enzyme from Saccharopolyspora spinosa also catalyzes the transamination of dTDP-4-keto-2,6-dideoxy-d-glucose.
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Organisms |
-Eubacteria |
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Family |
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Links |
Enzyme (activities) 2.6.1.110
BRENDA (activities) 2.6.1.110
KEGG (pathways) 2.6.1.110
PLPMDB (PLP mutants) 2.6.1.110
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References |
Articles on 2.6.1.110 |
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last changed |
2017/09/07 12:03 |
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