Activities | Families | Sequences | Fold types | References | Help
B6db activities: 2.6.1.110

2.6.1.110
Description dTDP-4-dehydro-2,3,6-trideoxy-D-glucose 4-aminotransferase
Alternative names dTDP-4-dehydro-2,3,6-trideoxy-D-glucose--glutamate aminotransferase;
dTDP-4-amino-2,3,4,6-tetradeoxy-β-D-threo-hexopyranose-oxoglutarate aminotransferase;
spnR (gene name)
Catalyzed reaction dTDP-4-dehydro-2,3,6-trideoxy-D-glucose + L-glutamate = dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose + 2-oxoglutarate
Cofactor Pyridoxal phosphate.
Comments The enzyme, isolated from the bacterium Saccharopolyspora spinosa, participates in the biosynthesis of forosamine.
Forosamine is a highly deoxygenated sugar found in several natural products, such as the insecticide spinosyns.

The enzyme from Saccharopolyspora spinosa also catalyzes the transamination of dTDP-4-keto-2,6-dideoxy-d-glucose.

Organisms -Eubacteria
 

Family 

2.6.1.110 (0)
 
Links Enzyme (activities) 2.6.1.110
BRENDA (activities) 2.6.1.110
KEGG (pathways) 2.6.1.110
PLPMDB (PLP mutants) 2.6.1.110
 
References Articles on 2.6.1.110
 
last changed 2017/09/07 12:03

B6db activities