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B6db activities:
Description Tryptophan aminotransferase.
Catalyzed reaction L-tryptophan + 2-oxoglutarate = indole-3-pyruvate + L-glutamate.
Cofactor Pyridoxal-phosphate.
Comments -!- Also acts on 5-hydroxytryptophan and, to a lesser extent on the phenyl amino acids.
The activity overlaps substantially with that of aromatic amino acid aminotransferase (
The tryptophan aminotransferases from plants produce indole-3-pyruvate used for the auxin biosynthetic pathway.
Organisms -Eubacteria -Plants -Fungi -Metazoa

Family (2)
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
 Stepanova AN, Robertson-Hoyt J, Yun J, Benavente LM, Xie DY, Dolezal K, Schlereth A, Jürgens G, Alonso JM. (2008) TAA1-mediated auxin biosynthesis is essential for hormone crosstalk and plant development Cell 133 177-91.

 Tao Y, Ferrer JL, Ljung K, Pojer F, Hong F, Long JA, Li L, Moreno JE, Bowman ME, Ivans LJ, Cheng Y, Lim J, Zhao Y, Ballaré CL, Sandberg G, Noel JP, Chory J. (2008) Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants Cell 133 164-7.

Articles on
last changed 2010/03/11 16:13

B6db activities