2.6.1.5
Description	Tyrosine aminotransferase
Alternative names	Tyrosine transaminase; TAT.
Catalyzed reaction	L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate.
Cofactor	Pyridoxal-phosphate.
Comments	-!- L-phenylalanine can act instead of L-tyrosine. -!- The mitochondrial enzyme may be identical with EC 2.6.1.1. -!- The three isoenzymic forms are interconverted by EC 3.4.22.4.
	May overlap with 2.6.1.57
Diseases	Tyrosinemia II (Richner-Hanhart syndrome)
Prosite	PROSITE; PDOC00098;
PDB	1BW0; 4IX8;
Organisms	-Eubacteria -Plants -Fungi -Metazoa -Human
Links	Enzyme (activities) 2.6.1.5 BRENDA (activities) 2.6.1.5 KEGG (pathways) 2.6.1.5 PLPMDB (PLP mutants) 2.6.1.5
References	Articles on 2.6.1.5
last changed	2017/12/22 09:55