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2.6.1.5 |
Description |
Tyrosine aminotransferase |
Alternative names |
Tyrosine transaminase;
TAT. |
Catalyzed reaction |
L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate. |
Cofactor |
Pyridoxal-phosphate. |
Comments |
-!- L-phenylalanine can act instead of L-tyrosine. -!- The mitochondrial enzyme may be identical with EC 2.6.1.1. -!- The three isoenzymic forms are interconverted by EC 3.4.22.4. |
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May overlap with 2.6.1.57 |
Diseases |
Tyrosinemia II (Richner-Hanhart syndrome) |
Prosite |
PROSITE; PDOC00098; |
PDB |
1BW0; 4IX8; |
Organisms |
-Eubacteria -Plants -Fungi -Metazoa -Human |
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Links |
Enzyme (activities) 2.6.1.5
BRENDA (activities) 2.6.1.5
KEGG (pathways) 2.6.1.5
PLPMDB (PLP mutants) 2.6.1.5
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References |
Articles on 2.6.1.5 |
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last changed |
2017/12/22 09:55 |
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