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2.6.1.59 |
Description |
dTDP-4-amino-4,6-dideoxygalactose aminotransferase |
Alternative names |
WecE (gene name); |
Catalyzed reaction |
dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate = dTDP-4-dehydro- 6-deoxy-D-galactose + L-glutamate. |
Cofactor |
Pyridoxal-phosphate. |
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WecE also transaminates TDP-4-keto 6-deoxy-D-mannose (TDP-D-Man4O), but not GDP-4-keto-6-deoxy-D-mannose (GDP-D-Man4O, the substrate of perosamine aminotransferase). |
Organisms |
-Eubacteria |
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Family |
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Links |
Enzyme (activities) 2.6.1.59
BRENDA (activities) 2.6.1.59
KEGG (pathways) 2.6.1.59
PLPMDB (PLP mutants) 2.6.1.59
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References |
Hwang, B.-Y.; Lee, H.-J.; Yang, Y.-H.; Joo, H.-S.; Kim, B.-G. (2004) Characterization and investigation of substrate specificity of the sugar aminotransferase WecE from E. coli K12 Chem Biol 211 915-25. Oashi, H.; Matsuhashi, M.; Matsuhashi, S. (1971) Thymidine diphosphate 4-acetamido-4,6-dideoxyhexoses. IV. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Pasteurella pseudotuberculosis J Biol Chem 246 2325-30. Matsuhashi, M.; Strominger, J. L. (1966) Thymidine diphosphate 4-acetamido-2,6-dideoxyhexoses. 3. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Escherichia coli strain B J Biol Chem 241 4738-44. Articles on 2.6.1.59 |
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last changed |
2019/06/18 13:17 |
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