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B6db activities:
Description O-ureido-L-serine synthase
Alternative names dcsD (gene name);
Catalyzed reaction O-acetyl-L-serine + hydroxyurea = O-ureido-L-serine + acetate
Cofactor Pyridoxal-phosphate.
Comments The enzyme participates in the biosynthetic pathway of D-cycloserine, an antibiotic substance produced by several Streptomyces species. Also catalyses EC, cysteine synthase.
The activity (at low level) is also displayed by pyrazolylalanine synthase and the like (see BRENDA).
PDB 3X43;
Organisms -Eubacteria

Family (0)
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
References Articles on
last changed 2019/06/21 13:07

B6db activities