Activities | Families | Sequences | Fold types | References | Help
B6db activities: 4.1.1.105

4.1.1.105
Description L-tryptophan decarboxylase
Alternative names psiD (gene name);
TDC (gene name)
Catalyzed reaction L-tryptophan = tryptamine + CO(2).
Cofactor Pyridoxal-phosphate or pyruvate.
Comments -!- The enzyme has been characterized from bacteria, plants, and fungi. Unlike EC 4.1.1.28, aromatic-L-amino-acid decarboxylase, this enzyme is specific for L-typtophan.
The L-Trp decarboxylase from the fungus Psilocybe (involved in the biosynthesis of the psychotropic psilocybin) is PLP-independent and presumably requires a pyruvoyl group.
PDB 4OBV;
Organisms -Eubacteria -Plants -Fungi
 

Family 

 
Links Enzyme (activities) 4.1.1.105
BRENDA (activities) 4.1.1.105
KEGG (pathways) 4.1.1.105
PLPMDB (PLP mutants) 4.1.1.105
 
References Articles on 4.1.1.105
 
last changed 2019/06/21 13:13

B6db activities