B6db activities : 4_1_1

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	4.1.1.105
Description	L-tryptophan decarboxylase
Alternative names	psiD (gene name); TDC (gene name)
Catalyzed reaction	L-tryptophan = tryptamine + CO(2).
Cofactor	Pyridoxal-phosphate or pyruvate.
Comments	-!- The enzyme has been characterized from bacteria, plants, and fungi. Unlike EC 4.1.1.28, aromatic-L-amino-acid decarboxylase, this enzyme is specific for L-typtophan.
	The L-Trp decarboxylase from the fungus Psilocybe (involved in the biosynthesis of the psychotropic psilocybin) is PLP-independent and presumably requires a pyruvoyl group.
PDB	4OBV;
Organisms	-Eubacteria -Plants -Fungi
Family	4.1.1.105_a (0) 4.1.1.105_b (0)

Links	Enzyme (activities) 4.1.1.105 BRENDA (activities) 4.1.1.105 KEGG (pathways) 4.1.1.105 PLPMDB (PLP mutants) 4.1.1.105

References	Articles on 4.1.1.105

last changed	2019/06/21 13:13

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