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4.1.1.105 |
Description |
L-tryptophan decarboxylase |
Alternative names |
psiD (gene name); TDC (gene name) |
Catalyzed reaction |
L-tryptophan = tryptamine + CO(2). |
Cofactor |
Pyridoxal-phosphate or pyruvate. |
Comments |
-!- The enzyme has been characterized from bacteria, plants, and fungi. Unlike EC 4.1.1.28, aromatic-L-amino-acid decarboxylase, this enzyme is specific for L-typtophan. |
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The L-Trp decarboxylase from the fungus Psilocybe (involved in the biosynthesis of the psychotropic psilocybin) is PLP-independent and presumably requires a pyruvoyl group. |
PDB |
4OBV; |
Organisms |
-Eubacteria -Plants -Fungi |
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Family |
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Links |
Enzyme (activities) 4.1.1.105
BRENDA (activities) 4.1.1.105
KEGG (pathways) 4.1.1.105
PLPMDB (PLP mutants) 4.1.1.105
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References |
Articles on 4.1.1.105 |
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last changed |
2019/06/21 13:13 |
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