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B6db activities:
Description 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase
Alternative names citryl-L-2,3-diaminopropionate decarboxylase;
SbnH (gene name);
Catalyzed reaction 2-((L-alanin-3-ylcarbamoyl)methyl)-2-hydroxybutanedioate <=> 2-((2-aminoethylcarbamoyl)methyl)-2-hydroxybutanedioate + CO(2)
Cofactor Pyridoxal-phosphate.
Comments The enzyme, characterized from the bacterium Staphylococcus aureus, participates in the biosynthesis of the siderophore staphyloferrin B.
Organisms -Eubacteria

Family (0)
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
 Tang J, Ju Y, Gu Q, Xu J, Zhou H (2019) Structural insights into substrate recognition and activity regulation of the key decarboxylase SbnH in staphyloferrin B biosynthesis J Mol Biol 431 4868-4881.

 Cheung J, Beasley FC, Liu S, Lajoie GA, Heinrichs DE (2009) Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus Mol Microbiol 74 1594-608.

Articles on
last changed 2019/10/23 12:50

B6db activities