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B6db activities: 4.1.1.17

4.1.1.17
Description Ornithine decarboxylase
Alternative names ODC.
Catalyzed reaction L-ornithine = putrescine + CO(2).
Cofactor Pyridoxal-phosphate.
Comments In mammals, ornithine decarboxylase catalyzes the rate-limiting step of the pathway leading to the production of polyamines, which play an essential role in cell proliferation.
Subfamily 1 includes enzymes that belong to the fold type III group and are mostly of eukaryotic origin.
Family 2 includes only eubacterial enzymes, beloging to the fold type I group.
Prosite PROSITE; PDOC00585; PROSITE; PDOC00685;
PDB 1ORD; 7ODC; 2TOD; 1D7K; 2PLK;
Organisms -Eubacteria -Plants -Fungi -Metazoa -Human
 
 
Links Enzyme (activities) 4.1.1.17
BRENDA (activities) 4.1.1.17
KEGG (pathways) 4.1.1.17
PLPMDB (PLP mutants) 4.1.1.17
 
References Articles on 4.1.1.17
 
last changed 2019/06/20 13:39

B6db activities