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B6db activities: 4.1.1.29

4.1.1.29
Description Sulfinoalanine decarboxylase
Alternative names Cysteine-sulfinate decarboxylase;
Cysteine sulfinic acid decarboxylase;
CSADCase.
Catalyzed reaction 3-sulfino-L-alanine = hypotaurine + CO(2).
Cofactor Pyridoxal-phosphate.
Comments -!- Also acts on l-cysteate.
The enzyme is involved in the biosynthesis of taurine, a sulfur-containing amino compound that apparently functions as a cytoprotectant and occurs at high concentration (550 mM) in most animal tissues.

The sequences of sulfinoalanine decarboxylases are strictly related to those of metazoan glutamate decarboxylases (4.1.1.15).

PDB 2JIS;
Organisms -Metazoa -Human
 
 
Links Enzyme (activities) 4.1.1.29
BRENDA (activities) 4.1.1.29
KEGG (pathways) 4.1.1.29
PLPMDB (PLP mutants) 4.1.1.29
 
References Articles on 4.1.1.29
 
last changed 2019/03/26 11:56

B6db activities