Activities | Families | Sequences | Fold types | References | Help
B6db activities:
Description 3-hydroxy-D-aspartate aldolase
Alternative names D-3-hydroxyaspartate aldolase;
3-hydroxy-D-aspartate glyoxylate-lyase (glycine-forming);
bhcC (gene name);
Catalyzed reaction threo-3-hydroxy-D-aspartate = glycine + glyoxylate
D-erythro-3-hydroxyaspartate = glycine + glyoxylate
Cofactor Pyridoxal-phosphate and Mn(II).
Comments A pyridoxal-phosphate protein. The enzyme, purified from the bacterium Paracoccus denitrificans IFO 13301, is strictly D-specific as to the α-position of the substrate, but accepts both the threo and erythro forms at the β-position. The erythro form is a far better substrate (about 100 fold). The enzyme can also accept D-allothreonine, D-threonine, erythro-3-phenyl-D-serine and threo-3-phenyl-D-serine.

Different from EC, erythro-3-hydroxy-L-aspartate aldolase.

Requires a divalent cation, such as Mg2+, Mn2+ or Co2+.

Organisms -Eubacteria

Family (0)
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
References Articles on
last changed 2019/11/19 11:19

B6db activities