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B6db activities:
Description Cysteine-S-conjugate beta-lyase
Alternative names Alkyl cysteine lyase.
Alkylcysteine lyase.
Cystathionine beta-lyase.
Cystine lyase.
L-cysteine-S-conjugate thiol-lyase (deaminating).
S-alkyl-L-cysteine lyase.
S-alkyl-L-cysteine sulfoxide lyase.
S-alkylcysteine lyase.
Catalyzed reaction RS-CH(2)-CH(NH(3)(+))COO(-) = RSH + NH(3) + pyruvate.
Cofactor Pyridoxal-phosphate.
Comments -!- R may represent aromatic compounds such as 4-bromobenzene and 2,4-dinitrobenzene.
Several PLP-dependent enzymes (mainly aminotransferases) show this activity, possibly as a side reaction.

In the public databases, sequences explicitly associated with this function also show kynurenine aminotransferase (EC and glutamine-phenylpyruvate transaminase (EC activities. These sequences have been included in the family.

Organisms -Eubacteria -Plants -Fungi -Metazoa
Links Enzyme (activities)
BRENDA (activities)
KEGG (pathways)
PLPMDB (PLP mutants)
References Articles on
last changed 2019/01/31 11:30

B6db activities