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4.4.1.14 |
| Description |
1-aminocyclopropane-1-carboxylate synthase. |
| Alternative names |
1-aminocyclopropane-1-carboxylic acid synthase.
Aminocyclopropanecarboxylate synthase.
ACC synthase. |
| Catalyzed reaction |
S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + methylthioadenosine. |
| Cofactor |
Pyridoxal-phosphate. |
| Comments |
-!- Catalyzes an alpha, gamma-elimination. |
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The enzyme carries out the rate-limiting step in the ethylene biosynthetic pathway in plants. |
| Prosite |
PROSITE; PDOC00098; |
| PDB |
1IAY; 1IAX; 1B8G; |
| Organisms |
-Plants -Fungi |
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Family |
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| Links |
Enzyme (activities) 4.4.1.14
BRENDA (activities) 4.4.1.14
KEGG (pathways) 4.4.1.14
PLPMDB (PLP mutants) 4.4.1.14
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| References |
Wang D, Fan J, Ranu RS. (2004) Cloning and expression of 1-aminocyclopropane-1-carboxylate synthase cDNA from rosa (Rosa x hybrida) Plant Cell Rep 22 422-9. Kakuta, Y.; Igarashi, T.; Murakami, T.; Ito, H.; Matsui, H.; Honma, M. (2001) 1-Aminocyclopropane-1-carboxylate synthase of Penicillium citrinum: primary structure and expression in Escherichia coli and Saccharomyces cerevisiae Biosci Biotechnol Biochem 65 1511-8. Capitani G.; Hohenester, E.; Feng, L.; Storici, P.; Kirsch, J.F.; Jansonius, J.N. (1999) Structure of 1-aminocyclopropane-1-carboxylate synthase, a key enzyme in the biosynthesis of the plant hormone ethylene J Mol Biol 294 745-56.. Sato, T.; Oeller, P. W.; Keller, J. A.; Theologis, A. (1991) The 1-aminocyclopropane-1-carboxylate synthase of Cucurbita. Purification, properties, expression in Escherichia coli, and primary structure determination by DNA sequence analysis J Biol Chem 266 3752-9. Van der Straeten, D.; Van Wiemeersch, L.; Goodman, H. M.; Van Montagu, M. (1990) Cloning and sequence of two different cDNAs encoding 1-aminocyclopropane-1-carboxylate synthase in tomato Proc Natl Acad Sci U S A 87 4859-63. |
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| last changed |
2008/04/25 17:41 |
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