B6db activities : 4_4_1

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	4.4.1.4
Description	Alliin lyase.
Alternative names	Alliinase. Cysteine sulphoxide lyase. L-cysteine sulfoxide lyase.
Catalyzed reaction	An S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2 aminocrylate.
Cofactor	Pyridoxal-phosphate.
Comments	The enzyme acts in the biochemical pathway leading to the compounds responsible for the characteristic flavor of garlic and onion.
	Additional_domain ALLN_ALLCE 125-450
PDB	1LK9;
Organisms	-Plants
Family	4.4.1.4 (7)

Links	Enzyme (activities) 4.4.1.4 BRENDA (activities) 4.4.1.4 KEGG (pathways) 4.4.1.4 PLPMDB (PLP mutants) 4.4.1.4

References	Kuettner, E.; Hilgenfeld, R.; Weiss, M. S. (2002) The active principle of garlic at atomic resolution J Biol Chem 277 46402-7.. Lancaster, J. E.; Shaw, M. L.; Joyce, M. D.; McCallum, J. A.; McManus, M. T. (2000) A novel alliinase from onion roots. Biochemical characterization and cDNA cloning Plant Physiol 122 1269-79. Manabe, T.; Hasumi, A.; Sugiyama, M.; Yamazaki, M.; Saito, K. (1998) Alliinase [S-alk(en)yl-L-cysteine sulfoxide lyase] from Allium tuberosum (Chinese chive)--purification, localization, cDNA cloning and heterologous functional expression Eur J Biochem 257 21-30. Rabinkov, A.; Zhu, X. Z.; Grafi, G.; Galili, G.; Mirelman, D. (1994) Alliin lyase (Alliinase) from garlic (Allium sativum). Biochemical characterization and cDNA cloning Appl Biochem Biotechnol 48 149-71. Articles on 4.4.1.4

last changed	2008/04/10 11:05

Family