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B6db activities: 5.4.3.8

5.4.3.8
Description Glutamate-1-semialdehyde 2,1-aminomutase
Alternative names Glutamate-1-semialdehyde aminotransferase;
HemL (gene name);
GSAT;
GSAM;
Catalyzed reaction (S)-4-amino-5-oxopentanoate = 5-aminolevulinate.
Cofactor Pyridoxal-phosphate or Pyridoxamine-phosphate.
Glutamate-1-semialdehyde 2,1-aminomutase is the second enzyme in the tetrapyrrole biosynthesis pathway found in most bacteria, in archaea and in plants (the first enzyme in the pathway is a most unusual glutamyl-tRNA reductase).
The enzyme has therefore paramount importance in the biosynthesis of compounds such as heme and chlorophyll.
Prosite PROSITE; PDOC00519;
PDB 2GSA; 3GSB; 4GSA; 5HDM;
Organisms -Eubacteria -Archea -Plants
 
 
Links Enzyme (activities) 5.4.3.8
BRENDA (activities) 5.4.3.8
KEGG (pathways) 5.4.3.8
PLPMDB (PLP mutants) 5.4.3.8
 
References Articles on 5.4.3.8
 
last changed 2019/06/20 13:03

B6db activities