B6db activities : 5_4_3

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	5.4.3.9
Description	Glutamate 2,3-aminomutase
Catalyzed reaction	L-glutamate <=> 3-aminopentanedioate
Cofactor	Pyridoxal-phosphate. S-adenosyl-L-methionine; [4Fe-4S] cluster
Comments	This enzyme is a member of the 'AdoMet radical' (radical SAM) family. It contains pyridoxal phosphate and a [4Fe-4S] cluster, which is coordinated by 3 cysteines and binds an exchangeable S-adenosyl-L- methionine molecule. During the reaction cycle, the AdoMet forms a 5'-deoxyadenosyl radical, which is regenerated at the end of the reaction.
Organisms	-Eubacteria
Family	5.4.3.9 (0)

Links	Enzyme (activities) 5.4.3.9 BRENDA (activities) 5.4.3.9 KEGG (pathways) 5.4.3.9 PLPMDB (PLP mutants) 5.4.3.9

References	Ruzicka, F.J.; Frey, P. A. (2007) Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes Biochim Biophys Acta 1774 286-96. Articles on 5.4.3.9

last changed	2014/02/19 11:46

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